By E.L. Cooper, A. Beschin, M. Bilej (editors)
This quantity first offers proof for the earthworm's immune process; the implications strongly recommend that definite molecules of the earthworm's immune procedure will be exploited as typical antibiotics - hence the biomedical functions. Earthworms have a powerful immune process on account that melanoma can't be precipitated in them, nor does it appear to happen in ordinary populations. Cytoxicity of melanoma cells has been tested on the subject of earthworm leukocytes dependent upon: constitution; telephone differentiation antigens; and serve as printed by way of FACS and mAbs.
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Extra info for A New Model for Analyzing Antimicrobial Peptides With Biomedical Applications (Nato: Life and Behavioural Sciences, 343)
2A). The percent of alkaline phosphatase in acidophils is moderate and that of a-esterase is low (Table 1). S. 32 Hamed et al. / Cytochemical Properties Fig. 2: Cytochemical properties of Eiseniafetida coelomocytes and chloragocytes. A: acid phosphatase (black arrow) in neutrophilic coelomocyte; B: alkaline phosphatase (white arrow) in basophilic coelomocyte; C: esterase in basophilic coelomocyte; D: alkaline phosphatase in acidophilic coelomocyte; E: acid phosphatase (black arrow) in chloragocyte; F: esterase on chloragocyte; (nu) nucleus.
Kobayashi et al, Lethal and non-lethal responses of spermatozoa from a wide variety of vertebrates and invertebrates to lysenin, a protein from the coelomic fluid of the earthworm Eisenia foetida, J. Exp. Zool. 286 (2000) 538-549. H. Kobayashi et al, Toxicity of coelomic fluid of the earthworm Eisenia foetida to vertebrates but not invertebrates: probable role of sphingomyelin, Comp. Biochem. Physiol 128C (2001) 401-411. S. Lange et al, Interaction of earthworm hemolysin with lipid membranes requires sphingolipids, J.
L. H. Mansour, Distribution of Thy-1 in invertebrates and ectothermic vertebrates. E. Reif and M. ), Cell Surface Antigen Thy-1. Immunology, Neurology, and Therapeutic Applications, Marcel Dekker, 1989, pp. 197-219.  Ph. Roch et al, Serological evidences for a membrane structure related to human B2 microglobulin expressed by certain earthworm leukocytes, Eur. J. Immunol. 13 (1983) 1037-1042.  D. Quagiino et al, Earthworm coelomocytes in vitro: cellular features and "granuloma" formation during cytotoxic activity against the mammalian tumor cell target K562, Eur.